During the last two trimesters of pregnancy

During the last two trimesters of pregnancy, glucose is spared for the fetus with increased concentration of fatty acids in plasma, which can create complications like preeclampsia, gestational diabetes mellitus, and preterm delivery 1. Preeclampsia is a pregnancy particular condition characterized by hypertension and proteinuria that transmits after conveyance. It is a trademark multisystem confusion of pregnancy, is a standout amongst the most well-known difficulties of pregnancy and is a main source of maternal and perinatal grimness and mortality 2.
Pre-eclampsia and its associated events are known to influence capacity of different organs required in metabolism of lipid and the lipoprotein.
It was reported that about 3-5% of pregnant mothers get pre-eclampsia, it leads to significant morbidity and mortality of the mother and her fetus worldwide 3.
Previous cardiovascular research studies reported that serum lipids have a direct effect on endothelial function So; abnormal serum lipid profiles are associated with endothelial dysfunction 4. Preeclampsia etiology is still unknown. The hypotheses currently accepted are the placental ischemia hypothesis, genetic hypothesis, the immune maladaptation and hypothesis of the imbalance between free oxygen radicals and scavengers in favor of oxidants 5.
A case control study carried out in the Department of Obstetrics and Gynecology at King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia, reported that; women with pre-eclampsia have higher serum triglyceride levels than normal pregnant women (P < 0.01), but there was insignificant difference as regards other serum lipids 6.
Another study comprised 30 normal pregnant women and 30 preeclampsia patients in their third trimester of pregnancy 7 found that; there was increased serum total cholesterol, triglycerides, LDL, cholesterol (P0.05) in HDL cholesterol in preeclampsia group than in normal pregnant women.
In this study, we aimed to measure the lipid profile among patients with preeclampsia.
Primary objective: to review the effects of abnormal lipid profile on antepartum, and postpartum risk.
Secondary objective: to correlate lipid profile findings among preeclampsia patients with the severity of proteinuria.